![]() ![]() Ī large number of prognostic factors for morbidity and mortality following PPU have been characterised. ![]() Timely and adequate identification of PPU patients at increased risk of reoperative surgery and adverse outcome is important, as this will enable a thorough and adequate planning of the pre-, intra-, and post-operative phases. Reoperation following surgery for PPU is associated with adverse outcome. Perforation of the gastro-intestinal wall by erosion from a peptic ulcer leads to acute peritonitis, and sepsis is believed to account for 40-50% of fatalities. ![]() Perforated peptic ulcer (PPU) is a surgical emergency with mortality rates reaching 25-30%. Patients undergoing reoperative surgery had a decreased 90-day survival. Patients undergoing reoperative surgery had a statistically significantly lower crude 90-day survival than patients without need of reoperative surgery 63.9% (83/124) versus 75.9% (457/602), p = 0.037.Ĭonclusion: In the present nationwide cohort study of PPU patients, no statistically significantly adjusted correlation between BMI and re-operation rates was found. No statistically significant adjusted association between underweight, overweight or obesity and re-operation was found (adjusted OR (95%CI): 0.456 (0.181-1.148), 1.468 (0.857-2.517), and 1.314 (0.663-2.601), respectively. Re-operative surgery was done in 124 patients (17.1%). The median age was 69.5 years (range: 18.2-101.7 years), 51.4% were women (n = 373), 78.4% (n = 569) of the patients had at least one co-existing disease, and 47.5% (n = 345) were categorised as American Society of Anesthesiologists (ASA) class ≥ 3. Results: A total of 726 patients were included. ![]() The association between BMI and reoperation are presented as crude and adjusted odds ratios (OR) with 95% confidence intervals (CIs). Outcome measures: Reoperation within 30 days of the primary surgical procedure and 90-day survival. Methods: This was a nationwide cohort study of all Danish patients who were surgically treated for benign gastric or duodenal PPU between 20. Introduction: The aim of the present nationwide Danish cohort study was to examine the association between body mass index (BMI) and reoperation in patients who are surgically treated for perforated peptic ulcer (PPU). ![]()
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